Sulfide solid electrolytes (SEs) have attracted ever-increasing attention due to their superior room-temperature ionic conductivity (∼10⁻² S cm⁻¹). Additionally, the integration of sulfide SEs and high-voltage cathodes is promising to achieve higher energy density. However, the incompatible interfaces between sulfide SEs and high-voltage cathodes have been one of the key factors limiting their applications. Therefore, this review presents a critical summarization of the interfacial issues in all-solid-state lithium batteries based on sulfide SEs and high-voltage cathodes and proposes strategies to stabilize the electrolyte/cathode interfaces. Moreover, the future research direction of electrolyte/cathode interfaces and application prospects of powder technology in sulfide-based ASSLBs were also discussed.